研究業績

• 論文
• 著書
• 特許権等知的財産権の取得及び申請状況
• 診療ガイドライン・政策提言等
• 獲得資金

論文

• Nambo R, Karashima S, Mizoguchi R, Konishi S, Hashimoto A, Aono D, Kometani M, Furukawa K, Yoneda T, Imamura K, Nambo H. Prediction and causal inference of cardiovascular and cerebrovascular diseases based on lifestyle questionnaires. Sci Rep. 2024 May 7;14(1):10492. doi: 10.1038/s41598-024-61047-w.
• Sawamura T, Karashima S, Ohbatake A, Higashitani T, Ohmori A, Sawada K, Yamamoto R, Kometani M, Katsuda Y, Yoneda T. Effects of Switching from Degludec to Glargine U300 in Patients with Insulin-Dependent Type 1 Diabetes: A Retrospective Study. Medicina (Kaunas). 2024 Mar 8;60(3):450. doi: 10.3390/medicina60030450.
• Nakano E, Mukai K, Fukuhara A, Otsuki M, Shimomura I, Ichijo T, Tsuiki M, Wada N, Yoneda T, Takeda Y, Oki K, Yamada T, Ogawa Y, Yabe D, Kakutani M, Sone M, Katabami T, Tanabe A, Naruse M; JPAS/JRAS Study Group. Primary aldosteronism patients with previous cardiovascular and cerebrovascular events have high aldosterone responsiveness to ACTH stimulation. Endocr J. 2024 Mar 14. doi: 10.1507/endocrj.EJ23-0659.
• Sawamura T, Kometani M, Karashima S, Yoneda T. Violaceous abdominal striae noted on physical examination: a clue to the diagnosis of Cushing's syndrome. BMJ Case Rep. 2024 Mar 8;17(3):e259687. doi: 10.1136/bcr-2024-259687.
• Sawamura T, Karashima S, Kometani M, Ohmori A, Yoneda T. Thyrotoxicosis Misdiagnosed as Long Covid by Telemedicine - A Cautionary Tale. Eur J Case Rep Intern Med. 2024 Jan 9;11(2):004206. doi: 10.12890/2024_004206.
• Tanaka Y, Nakata T, Aiga K, Etani T, Muramatsu R, Katagiri S, Kawai H, Higashino F, Enomoto M, Noda M, Kometani M, Takamura M, Yoneda T, Kakizaki H, Nomura A. Performance of Generative Pretrained Transformer on the National Medical Licensing Examination in Japan. PLOS Digit Health. 2024 Jan 23;3(1):e0000433. doi: 10.1371/journal.pdig.0000433.
• Takeda Y, Demura M, Kometani M, Karashima S, Aono D, Konishi S, Horike SI, Meguro-Horike M, Yoneda T, Takeda Y. Epigenetic alterations of 11beta-hydroxysteroid dehydrogenase 1 gene in the adipose tissue of patients with primary aldosteronism. Endocr J. 2024 Mar 28;71(3):245-252. doi: 10.1507/endocrj.EJ23-0103.
• Aiga K, Kometani M, Karashima S, Konishi S, Higashitani T, Aono D, Mai X, Usukura M, Asano T, Wakayama A, Noda Y, Koda W, Minami T, Kobayashi S, Murayama T, Yoneda T. A clinical assessment of portable point-of-care testing for quick cortisol assay during adrenal vein sampling. Sci Rep. 2023 Dec 16;13(1):22429. doi: 10.1038/s41598-023-49808-5.
• Aiga K, Kometani M, Aono D, Yoneda T. Recurrence of Primary Aldosteronism After Surgery in Aldosterone-producing Adenoma With KCNJ5 Gene Mutation. JCEM Case Rep. 2023;1(1):luac032. Published 2023 Jan 11. doi:10.1210/jcemcr/luac032
• Toyoda Y, Aiga K, Kometani M, Yoneda T. Acquisition of Interleukin-6 Production Ability Over Time With Pheochromocytoma. JCEM Case Rep. 2023;1(5):luad106. Published 2023 Sep 2. doi:10.1210/jcemcr/luad106
• Asaka H, Karashima S, Chujo D, et al. In vivo relationship between bound and free insulin in patients with diabetes having anti-insulin antibodies. Diabetol Int. 2023;14(4):427-433. Published 2023 Jun 20. doi:10.1007/s13340-023-00641-1
• Konishi S, Kometani M, Aiga K, et al. Using telemedicine to manage a patient with a hypertensive emergency due to pheochromocytoma. Endocrinol Diabetes Metab Case Rep. 2023;2023(3):23-0033. Published 2023 Jul 4. doi:10.1530/EDM-23-0033
• Mizoguchi R, Karashima S, Miyajima Y, et al. Impact of gut microbiome on the renin-aldosterone system: Shika-machi Super Preventive Health Examination results. Hypertens Res. 2023;46(10):2280-2292. doi:10.1038/s41440-023-01334-7
• Sawamura T, Karashima S, Ohmori A, et al. Fulminant type 1 diabetes developed after influenza split vaccination. Endocrinol Diabetes Metab Case Rep. 2023;2023(2):22-0342. Published 2023 May 4. doi:10.1530/EDM-22-0342
• Takeda Y, Demura M, Kometani M, Karashima S, Yoneda T, Takeda Y. Molecular and Epigenetic Control of Aldosterone Synthase, CYP11B2 and 11-Hydroxylase, CYP11B1. Int J Mol Sci. 2023;24(6):5782. Published 2023 Mar 17. doi:10.3390/ijms24065782
• Sawamura T, Karashima S, Kawahara H, Yoneda T. Abnormal findings in the basal ganglia: a diagnostic clue for patients with diabetic striatopathy. BMJ Case Rep. 2023;16(3):e254928. Published 2023 Mar 7. doi:10.1136/bcr-2023-254928
• Karashima S, Kawakami M, Nambo H, et al. A hyperaldosteronism subtypes predictive model using ensemble learning. Sci Rep. 2023;13(1):3043. Published 2023 Feb 21. doi:10.1038/s41598-023-29653-2
• Kobayashi H, Nakamura Y, Abe M, et al. Impact of a change to a novel chemiluminescent immunoassay for measuring plasma aldosterone on the diagnosis of primary aldosteronism. Endocr J. 2023;70(5):489-500. doi:10.1507/endocrj.EJ22-0585
• Yoneda M, Kometani M, Aiga K, et al. Impact of Conducting Adrenal Venous Sampling in the Morning Versus Afternoon in Primary Aldosteronism. J Endocr Soc. 2023;7(3):bvad007. Published 2023 Jan 14. doi:10.1210/jendso/bvad007
• Sawamura T, Karashima S, Aono D, et al. Adrenal Hemorrhaging in a Patient with Severe Obstructive Sleep Apnea Syndrome with Elevated Plasma ACTH Levels. Intern Med. 2023;62(15):2205-2208. doi:10.2169/internalmedicine.0895-22
• Yamakawa M, Karashima S, Takata R, et al. Comprehensive Steroid Assay with Non-Targeted Analysis Using Liquid Chromatography Ion Mobility Mass Spectrometry. Int J Mol Sci. 2022;23(22):13858. Published 2022 Nov 10. doi:10.3390/ijms232213858
• Mai X, Kometani M, Yoneda T. Spontaneous Remission of Primary Aldosteronism with Mineralocorticoid Receptor Antagonist Therapy: A Review. Int J Mol Sci. 2022;23(22):13821. Published 2022 Nov 10. doi:10.3390/ijms232213821
• Sakaguchi S, Okamoto R, Inoue C, et al. Associated factors and effects of comorbid atrial fibrillation in hypertensive patients due to primary aldosteronism. J Hum Hypertens. 2023;37(9):757-766. doi:10.1038/s41371-022-00753-2
• Miyajima Y, Karashima S, Ogai K, et al. Impact of gut microbiome on dyslipidemia in japanese adults: Assessment of the Shika-machi super preventive health examination results for causal inference. Front Cell Infect Microbiol. 2022;12:908997. Published 2022 Sep 2. doi:10.3389/fcimb.2022.908997
• Sawamura T, Karashima S, Ohmori A, et al. Hiccups as the first presentation of secondary adrenal insufficiency associated with advanced cervical cancer. Endocrinol Diabetes Metab Case Rep. Published online August 1, 2022. doi:10.1530/EDM-22-0286
• Aono D, Kometani M, Asano T, et al. A case of adrenocortical carcinoma diagnosed 9 years after the discovery of adrenal incidentaloma. Endocr J. 2022;69(12):1415-1421. doi:10.1507/endocrj.EJ22-0171
• Kometani M, Yoneda T, Karashima S, et al. Effect of Intraprocedural Cortisol Measurement on ACTH-stimulated Adrenal Vein Sampling in Primary Aldosteronism. J Endocr Soc. 2022;6(9):bvac104. Published 2022 Jul 26. doi:10.1210/jendso/bvac104
• Spyroglou A, Handgriff L, Müller L, et al. The metabolic phenotype of patients with primary aldosteronism: impact of subtype and sex - a multicenter-study of 3566 Caucasian and Asian subjects. Eur J Endocrinol. 2022;187(3):361-372. Published 2022 Jul 21. doi:10.1530/EJE-22-0040
• Hara S, Haneda E, Kawakami M, et al. Evaluating tubulointerstitial compartments in renal biopsy specimens using a deep learning-based approach for classifying normal and abnormal tubules. PLoS One. 2022;17(7):e0271161. Published 2022 Jul 11. doi:10.1371/journal.pone.0271161
• Nomura M, Kurihara I, Itoh H, et al. Association of cardiovascular disease risk and changes in renin levels by mineralocorticoid receptor antagonists in patients with primary aldosteronism. Hypertens Res. 2022;45(9):1476-1485. doi:10.1038/s41440-022-00960-x
• Nomura C, Nakano Y, Tanaka T, et al. Somatostatin Receptor-negative and Fluorodeoxyglucose-positron Emission Tomography-positive Lung Neuroendocrine Tumor G1 Exhibiting Cyclic Cushing's Syndrome. Intern Med. 2022;61(24):3693-3698. doi:10.2169/internalmedicine.9238-21
• Naruse M, Katabami T, Shibata H, et al. Japan Endocrine Society clinical practice guideline for the diagnosis and management of primary aldosteronism 2021. Endocr J. 2022;69(4):327-359. doi:10.1507/endocrj.EJ21-0508
• Sawamura T, Karashima S, Ohmori A, et al. Remitting Seronegative Symmetrical Synovitis with Pitting Edema Syndrome Worsen after the Administration of Dulaglutide. Medicina (Kaunas). 2022;58(2):289. Published 2022 Feb 14. doi:10.3390/medicina58020289
• Kawakami M, Karashima S, Morita K, et al. Explainable Machine Learning for Atrial Fibrillation in the General Population Using a Generalized Additive Model　- A Cross-Sectional Study. Circ Rep. 2021;4(2):73-82. Published 2021 Dec 28. doi:10.1253/circrep.CR-21-0151
• Kotake Y, Karashima S, Kawakami M, et al. Impact of salt intake on urinary albumin excretion in patients with type 2 diabetic nephropathy: a retrospective cohort study based on a generalized additive model. Endocr J. 2022;69(5):577-583. doi:10.1507/endocrj.EJ21-0447
• Nomura A, Noguchi M, Kometani M, Furukawa K, Yoneda T. Artificial Intelligence in Current Diabetes Management and Prediction. Curr Diab Rep. 2021;21(12):61. Published 2021 Dec 13. doi:10.1007/s11892-021-01423-2
• Naruse M, Tanabe A, Yamamoto K, et al. Adrenal Venous Sampling for Subtype Diagnosis of Primary Hyperaldosteronism. Endocrinol Metab (Seoul). 2021;36(5):965-973. doi:10.3803/EnM.2021.1192
• Yamagami K, Nomura A, Kometani M, et al. Early Detection of Symptom Exacerbation in Patients With SARS-CoV-2 Infection Using the Fitbit Charge 3 (DEXTERITY): Pilot Evaluation. JMIR Form Res. 2021;5(9):e30819. Published 2021 Sep 16. doi:10.2196/30819
• Takeda Y, Karashima S, Kometani M, Yoneda T. Penile and scrotal oedema along with urinary retention after insulin therapy. BMJ Case Rep. 2021;14(7):e240342. Published 2021 Jul 22. doi:10.1136/bcr-2020-240342
• Saito K, Kurihara I, Itoh H, et al. Subtype-specific trends in the clinical picture of primary aldosteronism over a 13-year period. J Hypertens. 2021;39(11):2325-2332. doi:10.1097/HJH.0000000000002924
• Kometani M, Yoneda T, Maeda Y, et al. Carcinoma of unknown primary origin with isolated adrenal metastasis: a report of two cases. Endocr J. 2021;68(10):1209-1215. doi:10.1507/endocrj.EJ21-0141
• Takeda Y, Demura M, Yoneda T, Takeda Y. DNA Methylation of the Angiotensinogen Gene, AGT, and the Aldosterone Synthase Gene, CYP11B2 in Cardiovascular Diseases. Int J Mol Sci. 2021;22(9):4587. Published 2021 Apr 27. doi:10.3390/ijms22094587
• Okamoto K, Ohno Y, Sone M, et al. Should Adrenal Venous Sampling Be Performed in PA Patients Without Apparent Adrenal Tumors?. Front Endocrinol (Lausanne). 2021;12:645395. Published 2021 Apr 12. doi:10.3389/fendo.2021.645395
• Kometani M, Yoneda T, Aono D, et al. Primary Aldosteronism with Parathyroid Hormone Elevation: A Single-center Retrospective Study. Intern Med. 2021;60(7):993-998. doi:10.2169/internalmedicine.5282-20
• Nakamaru R, Yamamoto K, Akasaka H, et al. Age-stratified comparison of clinical outcomes between medical and surgical treatments in patients with unilateral primary aldosteronism. Sci Rep. 2021;11(1):6925. Published 2021 Mar 25. doi:10.1038/s41598-021-86290-3
• Takeda Y, Demura M, Wang F, et al. Effect of potassium on DNA methylation of aldosterone synthase gene. J Hypertens. 2021;39(5):1018-1024. doi:10.1097/HJH.0000000000002742
• Higashitani T, Karashima S, Aono D, et al. A case of renovascular hypertension with incidental primary bilateral macronodular adrenocortical hyperplasia. Endocrinol Diabetes Metab Case Rep. Published online August 6, 2020. doi:10.1530/EDM-19-0163
• Kometani M, Yoneda T, Maeda Y, et al. Pheochromocytoma crisis with cyclic fluctuation in blood pressure mimics acute coronary syndrome. Endocrinol Diabetes Metab Case Rep. Published online September 23, 2020. doi:10.1530/EDM-20-0115
• Karashima S, Kometani M, Aono D, et al. Renal Artery Aneurysm Due to Fenestration of a Branch of the Renal Artery: A Case Study. J Endocr Soc. 2020;5(2):bvaa189. Published 2020 Nov 30. doi:10.1210/jendso/bvaa189
• Nakamaru R, Yamamoto K, Akasaka H, et al. Sex Differences in Renal Outcomes After Medical Treatment for Bilateral Primary Aldosteronism. Hypertension. 2021;77(2):537-545. doi:10.1161/HYPERTENSIONAHA.120.16449
• Sawamura T, Karashima S, Nagase S, et al. Effect of sodium-glucose cotransporter-2 inhibitors on aldosterone-to-renin ratio in diabetic patients with hypertension: a retrospective observational study. BMC Endocr Disord. 2020;20(1):177. Published 2020 Nov 30. doi:10.1186/s12902-020-00656-8
• Ohshima Y, Higashide T, Sakaguchi K, et al. The association of primary aldosteronism with glaucoma-related fundus abnormalities. PLoS One. 2020;15(11):e0242090. Published 2020 Nov 6. doi:10.1371/journal.pone.0242090
• Nagase S, Karashima S, Tsujiguchi H, et al. Impact of Gut Microbiome on Hypertensive Patients With Low-Salt Intake: Shika Study Results. Front Med (Lausanne). 2020;7:475. Published 2020 Sep 2. doi:10.3389/fmed.2020.00475
• Gondoh-Noda Y, Kometani M, Nomura A, et al. Feasibility of a Novel Mobile C-Reactive Protein-Testing Device Using Gold-Linked Electrochemical Immunoassay: Clinical Performance Study. JMIR Mhealth Uhealth. 2020;8(9):e18782. Published 2020 Sep 7. doi:10.2196/18782
• Kobayashi Y, Haze T, Yano Y, et al. Associations Between Changes in Plasma Renin Activity and Aldosterone Concentrations and Changes in Kidney Function After Treatment for Primary Aldosteronism. Kidney Int Rep. 2020;5(8):1291-1297. Published 2020 Jun 20. doi:10.1016/j.ekir.2020.06.012
• Hashimoto A, Takeda Y, Karashima S, et al. Impact of mineralocorticoid receptor blockade with direct renin inhibition in angiotensin II-dependent hypertensive mice. Hypertens Res. 2020;43(10):1099-1104. doi:10.1038/s41440-020-0458-5
• Ohno Y, Sone M, Inagaki N, et al. Nadir Aldosterone Levels After Confirmatory Tests Are Correlated With Left Ventricular Hypertrophy in Primary Aldosteronism. Hypertension. 2020;75(6):1475-1482. doi:10.1161/HYPERTENSIONAHA.119.14601
• Kobayashi H, Nakamura Y, Abe M, et al. Effect of cosyntropin during adrenal venous sampling on subtype of primary aldosteronism: analysis of surgical outcome. Eur J Endocrinol. 2020;182(3):265-273. doi:10.1530/EJE-19-0860
• Fujii Y, Takeda Y, Kurihara I, et al. Historical changes and between-facility differences in adrenal venous sampling for primary aldosteronism in Japan. J Hum Hypertens. 2020;34(1):34-42. doi:10.1038/s41371-019-0229-4
• Aono D, Kometani M, Karashima S, et al. Primary aldosteronism subtype discordance between computed tomography and adrenal venous sampling. Hypertens Res. 2019;42(12):1942-1950. doi:10.1038/s41440-019-0310-y
• Kometani M, Yoneda T, Demura M, et al. Genetic and epigenetic analyses of aldosterone-producing adenoma with hypercortisolemia. Steroids. 2019;151:108470. doi:10.1016/j.steroids.2019.108470
• Kobayashi H, Abe M, Nakamura Y, et al. Association Between Acute Fall in Estimated Glomerular Filtration Rate After Treatment for Primary Aldosteronism and Long-Term Decline in Renal Function. Hypertension. 2019;74(3):630-638. doi:10.1161/HYPERTENSIONAHA.119.13131
• Wada N, Shibayama Y, Yoneda T, et al. Lateralizing Asymmetry of Adrenal Imaging and Adrenal Vein Sampling in Patients With Primary Aldosteronism. J Endocr Soc. 2019;3(7):1393-1402. Published 2019 May 16. doi:10.1210/js.2019-00131
• Akehi Y, Yanase T, Motonaga R, et al. High Prevalence of Diabetes in Patients With Primary Aldosteronism (PA) Associated With Subclinical Hypercortisolism and Prediabetes More Prevalent in Bilateral Than Unilateral PA: A Large, Multicenter Cohort Study in Japan. Diabetes Care. 2019;42(5):938-945. doi:10.2337/dc18-1293
• Oka R, Nomura A, Yasugi A, et al. Study Protocol for the Effects of Artificial Intelligence (AI)-Supported Automated Nutritional Intervention on Glycemic Control in Patients with Type 2 Diabetes Mellitus. Diabetes Ther. 2019;10(3):1151-1161. doi:10.1007/s13300-019-0595-5
• Ohbatake A, Yagi K, Karashima S, et al. C-Peptide Area Under the Curve at Glucagon Stimulation Test Predicts Glucose Improvements by GLP-1 Receptor Analogue: A Retrospective Observational Study. Diabetes Ther. 2019;10(2):673-681. doi:10.1007/s13300-019-0586-6
• Karashima S, Yoneda T. Madelung disease in a 58-year-old man. CMAJ. 2019;191(2):E48. doi:10.1503/cmaj.180759
• Takeda Y, Umakoshi H, Takeda Y, et al. Impact of adrenocorticotropic hormone stimulation during adrenal venous sampling on outcomes of primary aldosteronism. J Hypertens. 2019;37(5):1077-1082. doi:10.1097/HJH.0000000000001964
• Wakabayashi Y, Oka R, Nakaya M, et al. Associations between Sleep-Disordered Breathing and Metabolic Risk Factors beyond Obesity. J Diabetes Res. 2018;2018:1567683. Published 2018 Oct 22. doi:10.1155/2018/1567683
• Karashima S, Tsuda T, Kometani M, et al. Severe Mitral Regurgitation As a Result of Rupture of Mitral Valve Chordae Tendineae in a Patient With Graves Disease. J Endocr Soc. 2018;2(11):1246-1250. Published 2018 Sep 17. doi:10.1210/js.2018-00173
• Umakoshi H, Tsuiki M, Yokomoto-Umakoshi M, et al. Correlation Between Lateralization Index of Adrenal Venous Sampling and Standardized Outcome in Primary Aldosteronism. J Endocr Soc. 2018;2(8):893-902. Published 2018 May 24. doi:10.1210/js.2018-00055
• Kometani M, Yoneda T, Aono D, et al. Impact of aldosterone-producing cell clusters on diagnostic discrepancies in primary aldosteronism. Oncotarget. 2018;9(40):26007-26018. Published 2018 May 25. doi:10.18632/oncotarget.25418
• Soma Y, Oka R, Fujii S, et al. Nihon Ronen Igakkai Zasshi. 2018;55(2):268-275. doi:10.3143/geriatrics.55.268
• Aono D, Oka R, Kometani M, et al. Insulin Secretion and Risk for Future Diabetes in Subjects with a Nonpositive Insulinogenic Index. J Diabetes Res. 2018;2018:5107589. Published 2018 Mar 22. doi:10.1155/2018/5107589
• Takeda Y, Demura M, Wang F, et al. Epigenetic Regulation of Aldosterone Synthase Gene by Sodium and Angiotensin II. J Am Heart Assoc. 2018;7(10):e008281. Published 2018 May 8. doi:10.1161/JAHA.117.008281
• Shibayama Y, Wada N, Naruse M, et al. The Occurrence of Apparent Bilateral Aldosterone Suppression in Adrenal Vein Sampling for Primary Aldosteronism. J Endocr Soc. 2018;2(5):398-407. Published 2018 Mar 22. doi:10.1210/js.2017-00481
• Sawada K, Karashima S, Kometani M, et al. Effect of sodium glucose cotransporter 2 inhibitors on obstructive sleep apnea in patients with type 2 diabetes. Endocr J. 2018;65(4):461-467. doi:10.1507/endocrj.EJ17-0440
• Karashima S, Tsuda T, Wakabayashi Y, et al. Ventricular Fibrillation Associated With Dynamic Changes in J-Point Elevation in a Patient With Silent Thyroiditis. J Endocr Soc. 2017;2(2):135-139. Published 2017 Dec 6. doi:10.1210/js.2017-00276
• Ohno Y, Sone M, Inagaki N, et al. Prevalence of Cardiovascular Disease and Its Risk Factors in Primary Aldosteronism: A Multicenter Study in Japan. Hypertension. 2018;71(3):530-537. doi:10.1161/HYPERTENSIONAHA.117.10263
• Oka R, Shibata K, Sakurai M, et al. Trajectories of Postload Plasma Glucose in the Development of Type 2 Diabetes in Japanese Adults. J Diabetes Res. 2017;2017:5307523. doi:10.1155/2017/5307523
• Kometani M, Yoneda T, Demura M, et al. Cortisol overproduction results from DNA methylation of CYP11B1 in hypercortisolemia. Sci Rep. 2017;7(1):11205. Published 2017 Sep 11. doi:10.1038/s41598-017-11435-2
• Karashima S, Kometani M, Tsujiguchi H, et al. Prevalence of primary aldosteronism without hypertension in the general population: Results in Shika study. Clin Exp Hypertens. 2018;40(2):118-125. doi:10.1080/10641963.2017.1339072
• Tada H, Kawashiri MA, Sakata K, et al. Renal glucosuria is not associated with atherosclerotic cardiovascular disease outcome in a general Japanese community. Atherosclerosis. 2017;261:111-116. doi:10.1016/j.atherosclerosis.2017.02.015
• Karashima S, Yoneda T, Kometani M, et al. Angiotensin II receptor blocker combined with eplerenone or hydrochlorothiazide for hypertensive patients with diabetes mellitus. Clin Exp Hypertens. 2016;38(7):565-570. doi:10.3109/10641963.2016.1151526
• Kometani M, Yoneda T, Demura M, et al. The Long-term Effect of Adrenal Arterial Embolization for Unilateral Primary Aldosteronism on Cardiorenovascular Protection, Blood Pressure, and the Endocrinological Profile. Intern Med. 2016;55(7):769-773. doi:10.2169/internalmedicine.55.5196

著書

• 米田　隆、米谷充弘、臼倉幹哉
  原発性アルドステロン症診療マニュアル改訂第3版:第3章　診断、D副腎静脈サンプリング、術中迅速コルチゾール測定の臨床応用　116-117,2017
  Representations of Psychological Functions of Peer Support Services for Diabetic Patients, Semantic Technology, Volume 8943 of the series Lecture Notes in Computer Science pp 311-318 2015Takeda Y ,Demura M, Yoneda T, Medical Treatment of Primary Aldosteronism, Primary Aldosteronism, pp 209-214 2014
  Osawa I, Ikeda M, Yoneda T, Takeda Y, Nakai M, Usukura M,Abe K,
• 米谷充弘、米田　隆
  臨床化学、原発性アルドステロン症診断の進歩、副腎静脈サンプリングにおける迅速コルチゾール測定の有用性
  Vol. 46　No.1、pp22-27,2017

特許権等知的財産権の取得及び申請状況

• 国内特許（第5590651号）「血液資料の品質評価方法」
• 米国特許 (US 8927219) 「Method for evaluation of quality of blood sample」

診療ガイドライン・政策提言等

• 原発性アルドステロン症ガイドライン作成委員（日本内分泌学会 平成23年12月～現在）
• 自民党　データヘルス推進特命委員会 第４回国民・患者視点のデータヘルスＷＧ 登壇

獲得資金

• 令和2年度　厚生労働科学研究費(循環器疾患・糖尿病等生活習慣病対策総合研究事業)
  〜オンライン特定保健指導・オンライン診療におけるPHR活用による行動変容に関する研究〜
• IoT等活用行動変容研究事業(H30~31 AMED)
  生活習慣病に対するオンライン保健指導サービスの構築と行動変容への検証研究
• 医工連携事業化推進事業(H29～H31 AMED)
  AVSキット等の国際的普及とFDA/TGA取得のための開発事業（児玉崇）
• 基盤研究(C)(H29～H31, 科学研究費補助金)
  生活習慣病における多機能携帯電話を用いた遠隔診療システムの構築（米田隆）
• 石川県次世代産業創造事業補助金(H29,石川県)
  在宅医療のモバイル型簡易測定システムの実用化
• 金沢大学附属病院臨床研究助成費(H26～H29, 金沢大学)
  迅速コルチゾール測定キットの国内外における薬事承認のための臨床研究
• 戦略的基盤技術高度化支援事業(H26～H27,中小企業庁(経産省))
  診断市場のPOCT化に資する新規蛍光剤を用いた高感度POCT装置の開発
• 基盤研究(C)(H25～H28,科学研究費補助金)
  地域医療における軽症糖尿病患者に対する在宅健康サービスの継続研究
• NEDO(H25,新エネルギー産業技術総合開発機構)
  副腎静脈サンプリングの成功率を高めるデバイスとリーダーの開発
• 基盤研究(C)(H22～H24,科学研究費補助金)
  地域医療における軽症糖尿病患者に対する在宅健康サービスの構築
• ふるさと携帯創出推進事業(H21年度(総務省))
  軽症の糖尿病患者に対する在宅健康サービスの構築